Medication
Gonadorelin
CompoundedPeptide
What it is
Gonadorelin is a synthetic form of gonadotropin-releasing hormone. In men's health it is sometimes prescribed alongside testosterone with the intent of maintaining testicular signalling during therapy.
How it is used
It is administered by injection on a frequent schedule owing to its short half-life. Protocols vary considerably between prescribers, and it is used at the discretion of the treating provider.
What a provider evaluates first
- Whether testicular signalling is a goal of the protocol
- Fertility intentions and baseline gonadotropins
- Tolerance of a more frequent injection schedule
Considerations and monitoring
- Compounded and not FDA-approved for this use
- Evidence in this context is limited; protocols are not standardised
- Requires frequent administration
Questions about gonadorelin
What is gonadorelin used for alongside TRT?
Gonadorelin is a synthetic gonadotropin-releasing hormone sometimes prescribed alongside testosterone with the intent of maintaining testicular signalling during therapy. It is compounded, not FDA-approved for this use, and protocols vary between prescribers. It requires frequent administration owing to its short half-life.
Part of TRT & Men's Health.