What side effects are associated with GLP-1 medications?

The most commonly reported are gastrointestinal — nausea, vomiting, diarrhoea, constipation and abdominal discomfort — and are most often noted when starting or increasing a dose. Serious risks described in the prescribing information for approved products in this class include pancreatitis, gallbladder disease and thyroid C-cell tumours in rodent studies. Discuss the full risk profile with your provider, and report any severe or persistent symptoms.